Archive for the ‘Infusion’ Category

coronary heart diseaseDefects on myocardial scans that improve on serial imaging are considered an expression of regional reductions in coronary blood flow. Resting 201Tl scans obtained in patients with known coronary heart disease at a time when they are angina-free can show reversible abnormalities of myocardial uptake, but only in the area of distribution of severely stenotic coronary arteries. Our findings indicate that similar abnormalities can frequently be identified in patients without known previous heart disease during the administration of vasopressin at low doses. Even individuals with insignificant or nonexistent coronary artery disease can show abnormal xaH scintigraphy in this setting. This phenomenon most likely reflects the capacity of vasopressin to increase coronary vascular resistance even at blood levels that are within the physiologic range.

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