Category: Small-Cell Carcinoma

Endobronchial Needle Aspiration in the Diagnosis of Small-Cell Carcinoma: Conclusion

In all five of our patients (Table 1), the forceps biopsy specimens of an endobronchial small-cell carcinoma were nondiagnostic due to either extensive mechanical crush artifact (cases 1, 2, 4, and 5) or to sampling error (case 3). The concurrently obtained cytologic specimens were all nondiagnostic, with the exception of a transtracheal needle aspirate (case…

Endobronchial Needle Aspiration in the Diagnosis of Small-Cell Carcinoma: Discussion

A 77-year-old man presented with a history of increasing dyspnea, malaise, weight loss, and dry cough over the preceding months. Chest radiograph and computed tomography demonstrated a large peripheral right lower lobe mass with hilar and mediastinal adenopathy. Bronchoscopy revealed extensive submucosal involvement of the right middle and lower lobe bronchus with tumor nodules protruding…

Endobronchial Needle Aspiration in the Diagnosis of Small-Cell Carcinoma: Case Reports

Case 1 A 49-year-old man presented with a 3-month history of cough and intermittent fever. The chest radiograph revealed left perihilar fullness and left upper lobe opacification. Computed tomography scan confirmed a 6.5X7.0-cm hilar mass with associated volume loss of the left lung. Bronchoscopy demonstrated an exophytic endobronchial tumor in the apical posterior segment of…

Endobronchial Needle Aspiration in the Diagnosis of Small-Cell Carcinoma: Methods

Since its introduction by Wang et al in the early 1980s, transbronchial needle aspiration (TBNA) via the fiberoptic bronchoscope has become a valuable adjunct in the evaluation of patients with lung cancer. The utility of TBNA in assessing mediastinal adenopathy and in staging lung cancer has been well documented.” Additionally, TBNA has been shown to…