Demonstrated Interactions
Fit voluteers experience a increase of 4-fold vardenafil AUC and 3-fold in Cmax when vardenafil (5 mg) was taken with a CYP3A4 inhibitor called Erythromycin 500 mg t.i.d.. Never take more than a 5 mg dose of vardenafil when combining it with the use of generic erythromycin.
Fit voluteers experience a increase of 10-fold vardenafil AUC and 4-fold in Cmax when vardenafil pills (5 mg) was taken with a CYP3A4 inhibitor called Ketoconazole 200 mg. Never take more than a 5 mg dose of canadian vardenafil when combining it with the use of generic ketoconazole.
10 mg of vardenafil was administered along witn 800 mg t.i.d. of the HIV protease inhibitor indinavir. The result was a 7-fold increase in vardenafil Cmax and 16-fold increase in vardenafil AUC. Vardenafil plasma level were about 4% of the maximum Cmax 24 hours after the drugs were administered. It is highly advised to avoid this combination. Never take more than a 5 mg dose of vardenafil drug when combining it with the use of indinavir.
Add A Comment