Effects
In one particular clinical trial, Visual fields, visual acuity, ERG latency, intraocular pressure, fundoscopic, nor slit lamp findings showed signs of being effected when visual functions were tested after a 40mg dose of vardenafil (two times the maximum recommended daily dosage). A minor group of patients spoke of color distortions in the blue/green and purple range, occurring one hour post dosing. After 6 hours the color distortions had been restored and did not return at 24 hours. There were no records of subjective visual symptoms on a majority of these patients. In separate trial, no association was made with dysfunction in intraocular pressure, visual acuity, or findings or slit lamp or fundoscopic examinations and once a day use of 10mg to 40mg doses of generic vardenafil over a 31 day period.
Effects on Blood Pressure
A slight, temporary drop in blood pressure has been attributed to taking vardenafil drug, but not, in most cases, to the extent of clinical concern. Supine systolic blood pressure had the maximum decrease, when being compared to placebo, of 6,9mmHg after 20 mg of vardenafil and 4.3 mmHg after 40 mg of vardenafil.
Effects on Cardiac Parameters
Volunteers, in fit physical condition, who swallowed a single dose of 80mg of cheap vardenafil (four times the maximum prescribed day to day dose) showed no effects on their ECGs of clinical relevance.
Effects on Exercise Performance in Patients with Coronary Artery Disease
The amount of treadmill exercise time compared to placebo, in a total of 39 males, between the ages of 48-77, with exercise induced ischaemia and coronary artery disease, were not altered in a placebo-controlled, two-period, cross-over trial after taking 10mg of vardenafil. The sum time of angina, compared to placebo, did not change. In the generic vardenafil group, the sum time of 1mm or more ST-segment depression was extended 15% in comparison to the placebo group (p<0.001). No patient was marked with any serious drug-related side effects during or after the trial.

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