LEVITRA® Tablets (Vardenafil, BAYER)

Sep-20-2008

Name of the Drug

Vardenafil (CAS number: 224785-90-4) in the form of vardenafil hydrochloride trihydrate. The empirical formula of vardenafil hydrochloride trihydrate: C23H32N6O4S.HCI.3H2O. Molecular weight: 579.1 g/mol.

Description

Vardenafil hydrochloride trihydrate, a nearly colorness solid, is 2-[ethoxy-5-(4-ethyl-piperazine-1-sulfonyl)-phenyl]-5-methyl-7-propyl-3H-imidazo[5,1-f][1,2,4]triazin-4-one hydrochloride trihydrate. Vardenafil hydrochloride trihydrate is soluble in 0.1M HCI and ethanol, freely soluble in methanol, and only slightly soluble in water and acetone.

LEVITRA comes in varying strength:

20 mg of vardenafil (23.705 mg of vardenafil hydrochloride trihydrate)
10 mg of vardenafil (11.852 mg of vardenafil hydrochloride trihydrate)
5 mg of vardenafil (5.926 mg of vardenafil hydrochloride trihydrate)

The above are drugs LEVITRA’S active ingredients, the tablets also contain: crospoyidone, colloidal anhydrous silica, microcrystalline cellulose, magnesium stearate, macrogol 400, titanium dioxide (CI77891), iron oxide red (CI77491), iron oxide yellow (CI77492).